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Anti-IMP3 Antibody (1F1-E10-D11)

Monoclonal antibody to detect IMP3
Catalog #: A1335
$265.00

Product Details

Cat # +Size A1335-100
Size 100 µg
Antibody Target IMP3
Alternate Name Insulin-like growth factor 2 mRNA-binding protein 3, IGF2 mRNA-binding protein 3, IMP-3, IGF-II mRNA-binding protein 3, KH domain-containing protein overexpressed in cancer, hKOC, VICKZ family member 3
Host Mouse
Antibody Type Monoclonal
Isotype Mouse IgG1
Immunogen Recombinant human IMP3 protein fragments expressed in E.coli
Accession # O00425
Gene ID 10643
Appearance Colorless liquid
Formulation In PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol
Purification Affinity purified
Species Reactivity Human
Application WB
Positive Control WB: MCF7, SKVO3, NTERA2, Jurkat, Hela and K562 cell lysates
Application & Usage WB; 1:1000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.


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