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Anti-IL1R2 Antibody

Polyclonal antibody to detect IL1R2 in Human samples.
Catalog #: A1778
$395.00

Product Details

Cat # +Size A1778-100
Size 100 µl
Antibody Target Interleukin-1 receptor type 2
Alternate Name IL1 Receptor II, IL1RB, CD121b, CDw121b, CD121 antigen-like family member B, Interleukin 1 receptor, Interleukin-1 receptor beta, Interleukin-1 receptor type 2, MGC137383, MGC47725, p68, Type II interleukin-1 receptor
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Accession # P27930
Gene ID 7850
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification Affinity purification
Species Reactivity Human
Application Immunohistochemistry (IHC), ELISA
Application & Usage IHC 1:25-1:200
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.


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