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Anti-IL-23α, Humanized Antibody (Td9)

Biosimilar to Tildrakizumab, monoclonal antibody that targets IL-23α
Catalog #: A2159
$455.00

Product Details

Cat # +Size A2159-100
Size 100 μg
Antibody Target IL-23α
Alternate Name P19, SGRF, IL-23, IL23A, IL23P19
Host Recombinant
Isotype IgG1, kappa
Immunogen Human IL-23α
Accession # DB14004
Appearance Colorless liquid
Formulation In PBS, pH 7.5
Purification Protein A purified
Species Reactivity Human
Handling The antibody solution should be gently mixed before use.
Storage Conditions -80°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The research-grade biosimilar is a humanized IgG1 monoclonal antibody that specifically targets the p19 subunit of IL-23. IL-23 is expressed and secreted by dendritic cells and macrophages. It belongs to the family of IL-12 cytokines and has two subunits: p40 that is shared with IL-12 and p19 that is unique for IL-23. IL-23 plays a critical role in maintaining and expanding Th17 cells. It also stimulates multiple innate immune cells such as myeloid cells and NK cells to produce proinflammatory cytokines that play an important role in the pathogenesis of inflammatory diseases such as Ulcerative Colitis (UC).


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