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Anti-IL-17α (Netakimab), Human IgG1 Antibody

The biosimilar is a humanized monoclonal antibody that targets IL-17α and inhibits IL-17α mediated inflammatory responses
Catalog #: A2206

Product Details

Cat # +Size A2206-100
Size 100 μg
Antibody Target IL-17α
Alternate Name BCD-085, BCD085, BCD 085, IL17a, IL17, CTLA8, IL-17, CTLA-8, IL-17A
Host Recombinant
Antibody Type Monoclonal
Isotype IgG1, kappa
Immunogen Human IL-17α
Appearance Colorless liquid
Concentration 1 mg/ml
Formulation In PBS, pH 7.5
Purification Protein A purified
Handling The antibody solution should be gently mixed before use.
Storage Conditions -80°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


The research-grade biosimilar is a humanized IgG1 monoclonal antibody that targets IL-17α and prevents the interaction with its receptor (IL-17R), thus blocking IL-17α mediated inflammatory and immune responses. IL-17α is a pro-inflammatory cytokine that plays an important role in inflammatory diseases such as psoriatic arthritis and ankylosing spondylitis (AS). In the heavy chain of the original antibody, VH variable domain is replaced with the VHH domain of Lama glama that possesses a long complementary determining region (CDR-H3) that allows the antibody to bind IL-17 with a higher affinity. The original antibody-drug has been approved to treat moderate-to-severe plaque psoriasis. Additionally, the drug is undergoing clinical trials to treat ankylosing spondylitis (AS).

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