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Anti-IL-12β, Human IgG1 Antibody

Biosimilar to Ustekinumab, monoclonal antibody that targets IL-12β
Catalog #: A2137
$455.00

Product Details

Cat # +Size A2137-100
Size 100 μg
Antibody Target IL-12β
Alternate Name IL-12β, IL12β, IL 12β
Host Recombinant
Antibody Type Monoclonal
Isotype IgG1, kappa
Immunogen human IL-12β
Accession # DB05679
Appearance Colorless liquid
Formulation In PBS pH 7.5
Purification Protein A purified
Species Reactivity Human
Application In vitro studies
Application & Usage In vitro studies
Handling The antibody solution should be gently mixed before use.
Storage Conditions -80ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The research-grade biosimilar is a human IgG1κ monoclonal antibody that was generated using human immunoglobulin (hu-Ig) transgenic mice. This monoclonal antibody specifically binds to the p40 subunit of IL-12. Interleukin 12 (IL-12) is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is expressed by activated macrophages that serve as an essential inducer of Th1 cell development. IL-12 is important for sustaining the population of memory and effector Th1 cells to mediate long-term protection to intracellular pathogens. Overexpression of IL-12 is observed in the central nervous system of patients with multiple sclerosis.


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