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Anti-HUR Antibody

Affinity purified rabbit polyclonal antibody to detect HUR expression in human, bovine, porcine and sheep samples
Catalog #: A2010
$295.00

Product Details

Size 100 µl
Antibody Target HUR
Alternate Name HUR; ELAV-like protein 1; Hu-antigen R; HuR
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen KLH-conjugated synthetic peptide targeting a sequence within the center region of human HUR
Accession # Q15717
Gene ID 1994
Appearance Colorless liquid
Formulation In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide
Purification Affinity purified
Species Reactivity Human, Porcine, Bovine, Sheep
Application Western Blotting
Application & Usage WB 1:500 - 1:1000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.


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