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Anti-HSPB1 (KO validated) Antibody

Rabbit polyclonal knockout validated antibody to detect expression of HSPB1 in huma, mouse and rat samples
Catalog #: A2074
$345.00

Product Details

Cat # +Size A2074-100
Size 100 μl
Antibody Target HSPB1
Alternate Name HSPB1; CMT2F; HEL-S-102; HMN2B; HS.76067; HSP27; HSP28; Hsp25; SRP27
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen Recombinant fusion protein targeting a sequence corresponding to aa 1-120 of human HSPB1
Accession # P04792
Gene ID 3315
Appearance Colorless liquid
Formulation In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Purification Affinity purified
Species Reactivity Human, Rat, Mouse
Application Western Blotting, Immunofluorescence (IF), Immunohistochemistry (IHC)
Application & Usage WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.


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