Anti-HER2, Humanized Antibody (Trz1)

Biosimilar to Trastuzumab, monoclonal antibody that targets HER2
Catalog #: A1046 | abID:

Product Details

Cat # +Size A1046-100
Size 100 µg
Antibody Target HER2
Alternate Name Neu, Ngl, Erbb2, Tkr1, Cd340, Her-2, Mln 19, HER-2/neu
Host Recombinant
Antibody Type Monoclonal
Isotype Human IgG1
Immunogen Recombinant human epidermal growth factor receptor 2 (HER2)
Accession # P04626
Gene ID 2064
Appearance Colourless liquid
Formulation 100 ug of antibody in Phosphate buffered saline, pH 7.4.
Purification IgG purified from CHO culture supernatant by protein A chromatography
Species Reactivity Human
Application Neutralization, ELISA
Application & Usage Neutralization : 1-20 μg/ml; ELISA: 2μg/ml
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C. Once thawed, store at 2-8℃
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


The research-grade biosimilar antibody is a recombinant humanized monoclonal immunoglobulin G1 kappa antibody that binds with high affinity and specificity to the extracellular domain of the HER2 receptor. A growth factor receptor gene, human epidermal growth factor receptor (HER2), is amplified in 25 to 30 % of breast cancers and in these cases the encoded protein is present in abnormally high levels in the malignant cells.

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Gerald Klanert, A cross-species whole genome siRNA screen in suspension-cultured Chinese hamster ovary cells identifies novel engineering targets. Sci Rep, June 2019;  31213643.
Lisa Nika. A HER2-Displaying Virus-Like Particle Vaccine Protects from Challenge with Mammary Carcinoma Cells in a Mouse Model. Vaccines (Basel) May-19. 31137559.
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