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Anti-Hepatitis C Virus Core Antigen Monoclonal Antibody (B1)

Monoclonal antibody targeting a key diagnostic marker for Hepatitis C
Catalog #: A2355
SKU-Size Size Price Qty
A2355-50 50 µl
$245.00
A2355-100 100 µl
$345.00
More Sizes Get Quote

Product Details

Antibody Target Hepatitis C Virus Core Antigen
Alternate Name Core protein p21 antibody, HCV core antigen antibody, HCV core protein antibody, Hepatitis C Virus core protein antibody
Host HEK 293 cells
Antibody Type Monoclonal
Isotype Mouse IgG2 kappa
Immunogen Epitope within amino acids 100-150 of HCVcAg
Appearance Liquid
Formulation In PBS with 1% BSA, 0.5 mM EDTA, 30% glycerol, and 0.03% Proclin
Purification Protein A Purification
Species Reactivity Hepatitis C Virus
Application ELISA
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Hepatitis C virus (HCV) is a positive, single-stranded RNA virus in the Flaviviridae family. The HCV core protein represents the first 191 amino acids of the viral precursor polyprotein. Polymerization of the HCV core protein forms the virus capsid, which houses its RNA genome. HCV is the cause of chronic hepatitis, liver cirrhosis, and some cancers in humans through blood and body fluid transmission. After translation, signal peptidases of the host cleave the precursor polyprotein and remove the signal peptide, which generates the HCV core protein antigen (HCVcAg). Its primary sequence is the most conserved sequence among the HCV proteins, making it a potential protein marker for HCV infection. The HCV core protein has been previously shown to circulate in the bloodstream of HCV-infected patients, therefore it serves as a well-developed marker for the diagnosis of infection.


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