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Anti-H4R3me2(sym) Antibody

Affinity purified rabbit polyclonal antibody to detect symmetric dimethylation of Histone H4 at Arginine 3 in human, mouse and rat samples
Catalog #: A2024
$310.00

Product Details

Size 100 µl
Antibody Target H4R3me2(sym)
Alternate Name FO108; H4; H4/n; H4F2; H4FN; HIST2H4; Histone H4; HIST1H4A; HIST2H4A
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen A synthetic methylation peptide targeting residues around Arginine 3 of human Histone H4
Accession # P62805
Gene ID 8370
Appearance Colorless liquid
Formulation In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Purification Affinity purified
Species Reactivity Human, Mouse, Rat
Application Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting
Application & Usage WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack poly A tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.


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