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New

Anti-H4R3me1 Antibody

Affinity purified rabbit polyclonal antibody to detect monomethylation of Histone H4 at Arginine 3 in human, mouse and rat samples
Catalog #: A2021
$350.00

Product Details

Size 100 µl
Antibody Target H4R3me1
Alternate Name HIST1H4B; H4/I; H4FI; histone H4; Histone H4; HIST1H4A; HIST2H4A; FO108; H4; H4/n; H4F2; H4FN; HIST2H4
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen A synthetic methylation peptide targeting residues around Arginine 3 of human Histone H4
Accession # P62805
Gene ID 8366
Appearance Colorless liquid
Formulation In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Purification Affinity purified
Species Reactivity Rat, Mouse, Human
Application Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting
Application & Usage IF 1:50 - 1:200, WB 1:500 - 1:2000, IHC 1:50 - 1:200
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack poly A tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.


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