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Product Details
| Size | 100 µl |
|---|---|
| Antibody Target | H3R2me1 |
| Alternate Name | H3.4; H3/g; H3FT; H3t; HIST3H3; Histone H3; HIST1H3A |
| Host | Rabbit |
| Antibody Type | Polyclonal |
| Isotype | IgG |
| Immunogen | A synthetic methylated peptide targeting residues around Arginine 2 of human Histone H3 |
| Accession # | Q16695 |
| Gene ID | 8290 |
| Appearance | Colorless liquid |
| Formulation | In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3 |
| Purification | Affinity purified |
| Species Reactivity | Human, Rat, Mouse |
| Application | Immunofluorescence (IF), Dot Blot, Western Blotting |
| Application & Usage | WB 1:500 - 1:2000, IF 1:50 - 1:200 |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20ºC |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack poly A tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
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