Product Details
| Cat # +Size | A2053-100 |
|---|---|
| Size | 100 µl |
| Antibody Target | H2BK5ac |
| Alternate Name | Histone H2B type 1-B (Histone H2B.1) (Histone H2B.f) (H2B/f), HIST1H2BB, H2BFF |
| Host | Rabbit |
| Antibody Type | Polyclonal |
| Isotype | IgG |
| Immunogen | Acetylated peptide sequence targeting residues around Lysine 5 of human Histone H2B type 1-B |
| Accession # | P33778 |
| Gene ID | 3018 |
| Appearance | Colorless liquid |
| Formulation | In 0.01 M PBS, 50% glycerol, 0.03% proclin 300, pH 7.4 |
| Purification | Antigen Affinity purified |
| Species Reactivity | Human |
| Application | Immunofluorescence (IF), Immunocytochemistry (ICC), ChiP |
| Application & Usage | ICC 1:20-1:200, IF 1:50-1:200 |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20ºC |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack poly A tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
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