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Anti-H2BK16ac Antibody

Affinity purified rabbit polyclonal antibody to detect acetylation of Histone H2B at Lysine 16 in human samples
Catalog #: A2050
$340.00

Product Details

Cat # +Size A2050-100
Size 100 µl
Antibody Target H2BK16ac
Alternate Name Histone H2B type 1-B (Histone H2B.1) (Histone H2B.f) (H2B/f), HIST1H2BB, H2BFF
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen Acetylated peptide sequence targeting residues around Lysine 16 of human Histone H2B type 1-B
Accession # P33778
Gene ID 3018
Appearance Colorless liquid
Formulation In 0.01 M PBS, pH 7.4, 50% Glycerol, 0.03% proclin 300
Purification Antigen Affinity purified
Species Reactivity Human
Application Immunofluorescence (IF), Immunocytochemistry (ICC), ChiP
Application & Usage ICC 1:20-1:200, IF 1:50-1:200
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack poly A tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.


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