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New

Anti-H2BK12me1 Antibody

Rabbit polyclonal antibody to detect monomethylation of Histone H2B at Lysine 12 in human samples
Catalog #: A2048
$325.00

Product Details

Size 100 µl
Antibody Target HIST1H2BC
Alternate Name Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l), HIST1H2BC; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI, H2BFL; H2BFH; H2BFG; H2BFA; H2BFK
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen A methylated peptide sequence targeting residues around Lysine 12 of human Histone H2B
Accession # P62807
Gene ID 8347
Appearance Colorless liquid
Formulation In 0.01 M PBS, 50% glycerol, 0.03% proclin 300, pH 7.4
Purification Antigen Affinity purified
Species Reactivity Human
Application Western Blotting, ChiP, Immunocytochemistry (ICC)
Application & Usage WB 1:100-1:1000, ICC 1:20-1:200
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. The protein has antibacterial and antifungal antimicrobial activity. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack poly A tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.


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