Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Anti-GOT1 Antibody

Polyclonal antibody to detect endogenous levels of GOT1 in human and rat samples.
Catalog #: A1272
$295.00

Product Details

Cat # +Size A1272-100
Size 100 µl
Antibody Target GOT1
Alternate Name Aspartate aminotransferase cytoplasmic; cAspAT; Cysteine aminotransferase cytoplasmic; Cysteine transaminase cytoplasmic; cCAT; Glutamate oxaloacetate transaminase 1; Transaminase A
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GOT1
Accession # P17174
Gene ID 2805
Appearance Colorless liquid
Formulation In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
Purification Affinity purified
Species Reactivity Human, Rat
Application WB
Positive Control WB: Jurkat, A549, PC12, H9C2 whole cell lysates.
Application & Usage WB; 1:500 – 1:1000
Handling The antibody solution should be gently mixed before use
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H2S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.
Yun Pyo Kang, Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer. eLife, May 2019; 31107239.
Yun Pyo Kang. Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer. eLife May-19. 31107239.
For more citations of this product click here