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Anti-Frizzled 9 Antibody

Polyclonal antibody to detect endogenous levels of Frizzled 9 in human, mouse and rat samples
Catalog #: A1633
$295.00

Product Details

Cat # +Size A1633-100
Size 100 µl
Antibody Target Frizzled 9
Alternate Name PROML1; Prominin-1; Antigen AC133; Prominin-like protein 1; CD133
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Frizzled 9
Accession # O00144
Gene ID 8326
Appearance Colorless liquid
Formulation In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
Purification Affinity purified
Species Reactivity Human, Mouse, Rat
Application WB
Positive Control WB: HEK293T; Raw264.7 ; PC12 whole cell lysates.
Application & Usage WB; 1:500 – 1:1000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Receptor for WNT2 that is coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. Plays a role in neuromuscular junction (NMJ) assembly by negatively regulating the clustering of acetylcholine receptors (AChR) through the beta-catenin canonical signaling pathway (By similarity). May play a role in neural progenitor cells (NPCs) viability through the beta-catenin canonical signaling pathway by negatively regulating cell cycle arrest leading to inhibition of neuron apoptotic process. During hippocampal development, regulates neuroblast proliferation and apoptotic cell death. Controls bone formation through non canonical Wnt signaling mediated via ISG15. Positively regulates bone regeneration through non canonical Wnt signaling.


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