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Anti-EGFR, Humanized Antibody (Pa5)

Biosimilar to Panitumumab, monoclonal antibody that targets EGFR
Catalog #: A1050
$425.00

Product Details

Cat # +Size A1050-100
Size 100 µg
Antibody Target EGFR
Alternate Name ERBB, ERRP, HER1, mENA, ERBB1, PIG61, NISBD2, EGFR
Host Recombinant
Antibody Type Monoclonal
Isotype Human IgG2k
Immunogen EGFR
Gene ID 1956
Appearance Colourless liquid
Formulation In PBS, pH 7.5
Purification Protein A purified
Species Reactivity Human
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

This biosimilar is a human monoclonal antibody against epidermal growth factor receptor (EGFR). The EGFR is a member of a subfamily of type I receptor tyrosine kinases, including EGFR (HERl, c-ErbB-l), HER2/neu, HER3, and HER4. EGFR is a transmembrane glycoprotein that is constitutively expressed in many normal epithelial tissues, including the skin and hair follicle. EGFR activation elicits essential downstream signaling pathways that are known to govern apoptosis, proliferation and differentiation of both normal and neoplastic cell types in a wide array of tissues. Overexpression of EGFR is also detected in many human cancers, including those of the colon and rectum.


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