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Anti-EGFR (Cetuximab), Chimeric Antibody

Monoclonal human IgG1 antibody against human EGFR
Catalog #: A1047
$415.00

Product Details

Cat # +Size A1047-100
Size 100 µg
Antibody Target EGFR
Alternate Name Erbitux
Host Human/Mouse chimeric
Antibody Type Monoclonal
Isotype Human IgG1
Immunogen Human A431 cells
Accession # Q147T7
Gene ID 1956
Appearance Colourless liquid
Formulation In Phosphate buffered saline, pH 7.4.
Purification IgG purified from murine cell culture supernatant by protein A chromatography
Species Reactivity Human
Application Neutralization, ELISA
Application & Usage Neutralization : 1-20 μg/ml; ELISA: 2μg/ml
Handling The antibody solution should be gently mixed before use.
Storage Conditions 4°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cetuximab is a recombinant human/mouse chimeric epidermal growth factor receptor (EGFR) monoclonal antibody. Epidermal growth factor receptor (EGFR) is a receptor found on both normal and tumor cells that is important for cell growth. Cetuximab is an EGFR inhibitor, used to treat cancer by blocking the activity of EGFR and keep cancer from growing. Cetuximab can form a bridge that trigger an immune response by binding to the EGFR on the tumor cells. It is used for the treatment of EGFR-expressing, metastatic colorectal cancer.


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