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Anti-E-Cadherin (CDH1) Rabbit Monoclonal Antibody

Rabbit monoclonal antibody to detect E-Cadherin in human samples.
Catalog #: A1126
$285.00

Product Details

Cat # +Size A1126-50
Size 50 µl
Antibody Target CDH1
Alternate Name P-cadherin, N-Cadherin, E-Cadherin, K-Cadherin, M-jadherin, R-Cadherin
Host Rabbit
Antibody Type Monoclonal
Isotype Rabbit IgG
Immunogen A peptide corresponding to Cadherin-1
Accession # P12830
Gene ID 999
Appearance Colorless liquid
Formulation In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Purification Affinity purified using protein A
Species Reactivity Human
Application IHC, WB
Positive Control WB: MCF-7 cells; IHC: human breast cancer tissues
Application & Usage IHC: 1:500 -1:1000 dilution; WB: 1:1000 - 1:2000 dilution
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cadherins comprise a family of Ca-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The most distal of cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxy terminal domains. The relative short intracellular domains interact with a variety of cytoplasmic proteins, such as β-catenin, to regulate cadherin function.


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