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Anti-Dlx-5 Antibody

Polyclonal antibody to detect endogenous levels of Dlx-5 in human, mouse and rat samples
Catalog #: A1626

In stock

$395.00

Product Details

Cat # +Size A1626-100
Size 100 µl
Antibody Target Dlx-5
Alternate Name Homeobox protein DLX-5 antibody
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthesized peptide derived from human Dlx-5 (60-140 aa)
Accession # P56178
Gene ID 1749
Appearance Colorless liquid
Formulation In PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Purification Affinity purified
Species Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ELISA
Positive Control WB:
Application & Usage WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding.


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