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Anti-DCTN1 Antibody (3D5-C6-D5)

Monoclonal antibody to detect DCTN1
Catalog #: A1341
$265.00

Product Details

Cat # +Size A1341-100
Size 100 µg
Antibody Target Dynactin subunit 1
Alternate Name Dynactin subunit 1, 150 kDa dynein-associated polypeptide, DAP-150, DP-150, p135, p150-glued
Host Mouse
Antibody Type Monoclonal
Isotype Mouse IgG1
Immunogen Recombinant human DCTN1 protein fragments expressed in E.coli
Accession # Q14203
Gene ID 1639
Appearance Colorless liquid
Formulation In PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol
Purification Affinity purified
Species Reactivity Human
Application WB
Positive Control WB: K562, MCF7, 293T and HeLa cell lysates, IP: HeLa cells
Application & Usage WB; 1:500
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Plays a key role in dynein-mediated retrograde transport of vesicles and organelles along microtubules by recruiting and tethering dynein to microtubules. Binds to both dynein and microtubules providing a link between specific cargos, microtubules and dynein. Essential for targeting dynein to microtubule plus ends, recruiting dynein to membranous cargos and enhancing dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Can also act as a brake to slow the dynein motor during motility along the microtubule.


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