Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Anti-D2HGDH Antibody

Polyclonal Antibody to detect D2HGDH in human samples
Catalog #: A1382
SKU-Size Size Price Qty
A1382-30T 30 µg
$89.00
A1382-100 100 µg
$265.00
More Sizes Get Quote

Product Details

Antibody Target D2HGDH
Alternate Name D-2-hydroxyglutarate dehydrogenase, D2HGDH, D2HGD, D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Full-length D2HGDH from Acidaminococcus fermentans
Appearance Colorless liquid
Formulation In PBS pH 7.2, 30% glycerol, 0.5% BSA, 0.5 mM EDTA and 0.03% proclin
Purification Affinity purified
Species Reactivity Acidaminococcus fermentans
Application Western blot
Positive Control Western blot
Application & Usage Western blot: 1-4 µg/ml
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

D-2-hydroxyglutarate (D2HG) level is significantly increased in metabolic diseases and various cancers such as acute myeloid leukemia. Studies suggest that the detection of D2HG serves as a biomarker assay related to IDH (isocitrate dehydrogenase) mutations. D2HGDH is a special NAD-dependent enzyme which reacts with D2HG specifically and converts D2HG to α-ketoglutarate. D2HGDH is a key enzyme to distinguish between two metabolites, D2HG and L-2-hydroxyglutarate (L2HG), during biomarker assays.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.