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Anti-CRKL Antibody

Affinity purified rabbit polyclonal antibody to detect CRKL expression in human, mouse and rat samples
Catalog #: A2041
$345.00

Product Details

Size 100 µl
Antibody Target CRKL
Alternate Name Crk-like protein
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen KLH-conjugated synthetic peptide targeting a sequence within the center region of human CRKL.
Accession # P46109
Gene ID 1399
Appearance Colorless liquid
Formulation In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide
Purification Affinity purified
Species Reactivity Rat, Mouse, Human
Application Western Blotting, Immunohistochemistry (IHC), Immunofluorescence (IF)
Application & Usage WB 1:500 - 1:1000, IHC 1:50 - 1:100, IF 1:100 - 1:500
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.


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