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Anti-Cripto 1 Antibody

Polyclonal antibody to detect endogenous levels of Cripto 1 in human, mouse and rat samples
Catalog #: A1672

In stock

$395.00

Product Details

Cat # +Size A1672-100
Size 100 µl
Antibody Target Cripto 1
Alternate Name CRIPTO; Teratocarcinoma-derived growth factor 1; Cripto-1 growth factor; CRGF; Epidermal growth factor-like cripto protein CR1
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen A synthesized peptide derived from human Cripto 1
Accession # P13385
Gene ID 6997
Appearance Colorless liquid
Concentration 1 mg/ml
Formulation In phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol
Purification Affinity purified
Species Reactivity Human, Mouse, Rat
Application WB,IHC, ELISA
Positive Control WB: NCCIT lysate, IHC: Human lung tissue
Application & Usage WB 1:500-1:2000 IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated TDGF1 acts as a Nodal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells. Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.


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