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Anti-CK-13 Antibody

Polyclonal antibody to detect endogenous levels of CK-13 in human, mouse and rat samples
Catalog #: A1707
$395.00

Product Details

Cat # +Size A1707-100
Size 100 µl
Antibody Target CK-13
Alternate Name Cytokeratin-13, CK-13 Keratin-13, K13, KRT13, Keratin, type I cytoskeletal 13
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen Recombinant protein of human KRT13
Accession # P13646
Gene ID 3860
Appearance Colorless liquid
Concentration 0.4 mg/mL
Formulation In PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Purification Affinity purified
Species Reactivity Rat,Mouse,Human
Application Immunohistochemistry (IHC),ELISA
Application & Usage ELISA,IHC 1:50-1:200
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described.


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