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Anti-CHRDL1 Antibody (3H1-F6-A10)

Monoclonal antibody to detect endogenous levels of CHRDL1 in human samples
Catalog #: A1625

In stock

$395.00

Product Details

Cat # +Size A1625-100
Size 100 µl
Antibody Target CHRDL1
Alternate Name Chordin-like protein 1, Neuralin-1, Neurogenesin-1, Ventroptin, NRLN1
Host Mouse
Antibody Type Monoclonal
Isotype Mouse IgG
Immunogen Purified recombinant human CHRDL1 protein fragments expressed in E.coli.
Accession # Q9BU40
Gene ID 91851
Appearance Colorless liquid
Formulation In PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Purification Affinity purified
Species Reactivity Human
Application WB, ELISA
Positive Control WB: Human eye and HeLa cell lysate, IF/ICC: HeLa cells
Application & Usage WB: WB 1:500-1:2000, ELISA 1:10000-20000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation . May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development.


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