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Anti-CD80, Human IgG1, Lambda Antibody

Biosimilar to Galiximab, monoclonal antibody that targets CD80
Catalog #: A2011
SKU-Size Size Price Qty
A2011-50 50 μg
$245.00
A2011-100 100 μg
$395.00
More Sizes Get Quote

Product Details

Antibody Target CD80
Alternate Name B7-1; T-lymphocyte activation antigen CD80; Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7
Host Recombinant
Antibody Type Monoclonal
Isotype Human IgG1, lambda
Immunogen The biosimilar was prepared by immunizing cynomolgus monkeys with recombinant CD80 antigen. The variable regions of the light and heavy chains were then cloned by being incorporated into a cassette vector (N5LG1) containing human constant region genes and
Accession # P33681
Gene ID 941
Appearance Colorless liquid
Formulation Supplied in PBS, pH 7.5
Species Reactivity Human
Application Block, Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting, Immunoprecipitation (IP), Modulate, Flow Cytometry, ELISA
Handling The antibody solution should be gently mixed before use.
Storage Conditions Aliquot and store at -20 °C to -80 °C. Avoid repeated freeze-thaw cycles
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

This biosimilar is a primatized mAb which consists of human constant and primate (cynomolgus macaque) variable regions and binds specifically to CD80. CD80 is a surface glycoprotein and a member of the B7 family of co-stimulatory molecules. CD80 antigen regulates T cell activation (through interacting with CD28 or CD152) and is expressed transiently in antigen-presenting cells, T cells and normal B cells, and expressed constitutively on various subtypes of B-cell lymphomas.


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