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Anti-CD71 / Transferrin Receptor Antibody (TFRC/1817)

Monoclonal Antibody to detect CD71 / TfR in human samples
Catalog #: A1559

In stock

$395.00

Product Details

Cat # +Size A1559-100
Size 100 µg
Antibody Target CD71 / TfR
Alternate Name Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR, Transferrin receptor protein 1, TR, TfR, TfR1, Trfr, T9, CD71, sTfR, TFRC
Host Mouse
Antibody Type Monoclonal
Isotype Mouse / IgG2b, kappa
Immunogen Recombinant human TFRC protein fragment (aa94-212) (exact sequence is proprietary)
Accession # P02786
Gene ID 7037
Appearance Colorless liquid
Formulation In 10 mM PBS with 0.05% BSA & 0.05% azide
Purification Protein A/G purification
Species Reactivity Human
Application FC, IF, WB, IHC
Positive Control IHC: Human Placenta, WB: A) Jurkat (B) HeLa (C) MCF-7 & (D) K562 Cell
Application & Usage FC: 0.5-1 µg/1X106 cells in 0.1 ml, IF: 1-2 µg/ml, IHC: 1-2 µg/ml for 30 minutes at RT, WB: 0.5-1.0 µg/ml
Handling The antibody solution should be gently mixed before use
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

It recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This mAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.


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