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Anti-CD68 Antibody (C68/684)

Monoclonal Antibody to detect CD68 in human samples
Catalog #: A1558

In stock

$395.00

Product Details

Cat # +Size A1558-100
Size 100 µg
Antibody Target CD68
Alternate Name GP110, LAMP4, Microsialin, Macrosialin, SCARD1, Scavenger Receptor Class D Member-1
Host Mouse
Antibody Type Monoclonal
Isotype Mouse / IgG1, kappa
Immunogen Recombinant human CD68 protein
Accession # P34810
Gene ID 968
Appearance Colorless liquid
Formulation In 10 mM PBS with 0.05% BSA & 0.05% azide
Purification Protein A/G purification
Species Reactivity Human and Monkey
Application FC, IF, IHC
Positive Control IHC: human Histiocytoma , human Tonsil
Application & Usage FC: 0.5-1 µg/1X106 cells in 0.1 ml, IF: 0.5-1 µg/ml, IHC: 0.25-0.5 µg/ml for 30 minutes at RT
Handling The antibody solution should be gently mixed before use
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

This antibody recognizes a glycoprotein of 110 kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.


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