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Anti-CD50 / ICAM-3 Antibody (Clone 186-2G9)

Monoclonal Antibody to detect CD50 / ICAM-3 in human samples
Catalog #: A1551

In stock

$395.00

Product Details

Cat # +Size A1551-100
Size 100 µg
Antibody Target CD50 / ICAM-3
Alternate Name Intercellular adhesion molecule 3, ICAM-3, CDw50, ICAM-R, CD50, ICAMR
Host Mouse
Antibody Type Monoclonal
Isotype Mouse / IgG2b, kappa
Immunogen Stimulated human leukocytes
Accession # P32942
Gene ID 3385
Appearance Colorless liquid
Formulation In 10 mM PBS with 0.05% BSA & 0.05% azide
Purification Protein A/G purification
Species Reactivity Human
Application FC, IF, IHC
Positive Control IHC: human Tonsil
Application & Usage FC: 0.5-1 µg/1X106 cells in 0.1 ml, IF: 0.5-1 µg/ml, IHC: 0.5-1 µg/ml for 30 minutes at RT
Handling The antibody solution should be gently mixed before use
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Recognizes the D1 domain of an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This mAb is excellent for staining of formalin/paraffin tissues.


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