Product Details
| Cat # +Size | A1387-100 |
|---|---|
| Size | 100 µl |
| Antibody Target | CD47 |
| Alternate Name | Leukocyte surface antigen CD47, Antigenic surface determinant protein OA3, Integrin-associated protein, IAP, Protein MER6 |
| Host | Rabbit |
| Antibody Type | Polyclonal |
| Isotype | Rabbit IgG |
| Immunogen | Synthetic peptide |
| Accession # | Q08722 |
| Gene ID | 961 |
| Appearance | Colorless liquid |
| Formulation | In PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
| Purification | Affinity purified |
| Species Reactivity | Human |
| Application | Western blot, IHC, ELISA |
| Positive Control | WB: 3T3 cells, IHC: human lymph node |
| Application & Usage | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000 |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
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