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Product Details
| Cat # +Size | A1592-50 |
|---|---|
| Size | 50 µl |
| Antibody Target | CD44 |
| Alternate Name | CD44, homing cell adhesion molecule, cell adhesion molecule, LHR, MDU2, MDU3, MIC4 |
| Host | Rabbit |
| Antibody Type | Monoclonal |
| Isotype | Rabbit IgG |
| Immunogen | A peptide corresponding to the extracellular domain of human CD44 |
| Accession # | P16070 |
| Gene ID | 960 |
| Appearance | Colorless liquid |
| Formulation | In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide |
| Purification | Affinity purified |
| Species Reactivity | Human |
| Application | WB, IHC |
| Positive Control | WB, IHC |
| Application & Usage | WB: 1:1000-1:2000; IHC: 1:1000-1:5000 |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20 °C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
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