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Anti-CD4, Humanized Antibody (Ib7)

Biosimilar to Ibalizumab, monoclonal antibody that targets CD4
Catalog #: A2251
$465.00

Product Details

Cat # +Size A2251-100
Size 100 μg
Antibody Target CD4
Alternate Name CD4mut, CD4, CD4 Molecule, T-Cell Surface Glycoprotein CD4, T-Cell Surface Antigen T4/Leu-3, CD4 Antigen (P55), CD4 Receptor, CD4 Antigen
Host Recombinant
Antibody Type Monoclonal
Isotype IgG4, kappa
Immunogen Human CD4
Accession # DB12698
Gene ID 920
Appearance Colorless liquid
Formulation In PBS, pH 7.5
Purification Protein A purified
Species Reactivity Human
Handling The antibody solution should be gently mixed before use.
Storage Conditions -80°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The research-grade biosimilar is a humanized monoclonal antibody that targets CD4. CD4 is a primary receptor for the human immunodeficiency virus (HIV-1). HIV-1 enters target cells by binding to CD4 via envelope glycoprotein (gp120). As a result, the CD4/gp120 complex enables the binding of gp120 to another cell receptor CCR5 or CXCR4. This interaction allows gp41 mediated fusion of viral envelope with the target cell membrane.


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