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Anti-CD4 (Campath-9H), Rabbit IgG, kappa Antibody

Recombinant monoclonal antibody manufactured using Recombinant Platform with variable regions from the hybridoma YNB46.1.8 (Campath 9-H) to detect CD4 expression in humans
Catalog #: A2012
$455.00

Product Details

Size 200 μg
Antibody Target CD4
Alternate Name Cluster of differentiation 4; T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3
Host RecombinantAppearance: Colorless liquid
Antibody Type Monoclonal
Isotype Rabbit IgG, kappa
Immunogen Rat T-cell line (NB2) transfected with the human CD4
Accession # P01730
Gene ID 920
Appearance Colorless liquid
Concentration 1 mg/ml
Formulation In PBS with 0.02% Proclin 300
Purification Protein A affinity purified
Species Reactivity Human
Application Western Blotting, IHC-Fr, Flow Cytometry, Immunohistochemistry (IHC)
Application & Usage WB, FC, IHC, IHC-Fr
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

CD4 gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Anti-CD4 (Campath-9H) monoclonal antibody recognizes the 55 kDa human CD4 cell surface antigen. This chimeric rabbit antibody was made using the variable domain sequences of the original rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.


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