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Anti-CD4, Rabbit IgG kappa Antibody (YNB46.1.8)

Biosimilar to Campath-9H, monoclonal antibody that targets CD4
Catalog #: A2012
SKU-Size Size Price Qty
A2012-50 50 μg
$245.00
A2012-100 100 μg
$395.00
More Sizes Get Quote

Product Details

Antibody Target CD4
Alternate Name Cluster of differentiation 4; T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3
Host Recombinant
Antibody Type Monoclonal
Isotype Rabbit IgG, kappa
Accession # P01730
Gene ID Rat T-cell line (NB2) transfected with the human CD4
Appearance Colorless liquid
Formulation Supplied in PBS, pH 7.5
Species Reactivity Human
Application Western Blotting, IHC-Fr, Flow Cytometry, Immunohistochemistry (IHC)
Handling The antibody solution should be gently mixed before use.
Storage Conditions Aliquot and store at -20 °C to -80 °C. Avoid repeated freeze-thaw cycles
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

CD4 gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Anti-CD4 monoclonal antibody recognizes the 55 kDa human CD4 cell surface antigen. This chimeric rabbit antibody was made using the variable domain sequences of the original rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.


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