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Anti-CD20 (Rituximab), Chimeric Antibody

Monoclonal human IgG1 antibody against human CD20
Catalog #: A1049
$415.00

Product Details

Cat # +Size A1049-100
Size 100 µg
Antibody Target CD20
Alternate Name MabThra
Host Recombinant
Antibody Type Monoclonal
Isotype Human IgG1
Immunogen CD20
Accession # P11836
Gene ID 54474
Appearance Colourless liquid
Formulation In Phosphate buffered saline, pH 7.4.
Purification Protein A chromatography.
Species Reactivity Human
Application Neutralization, ELISA
Application & Usage Neutralization: 1-20 μg/ml; ELISA: 2μg/ml
Handling The antibody solution should be gently mixed before use.
Storage Conditions Store at -20℃. Once thawed, keep it at 4℃
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Rituximab, a chimeric monoclonal antibody targeted against the pan-B-cell marker CD20. Mechanisms of cell destruction that have been demonstrated to be activated by rituximab binding to CD20 include direct signaling of apoptosis, complement activation and antibody dependent cellular cytotoxicity. Rituximab is a mainstay in the therapy for a broad variety of B-cell malignancies.


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