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Anti-CD15 / FUT4 Antibody (FUT4/815 + BRA-4F1)

Monoclonal Antibody to detect CD15 / FUT4 in human samples
Catalog #: A1476

In stock

$395.00

Product Details

Cat # +Size A1476-100
Size 100 µg
Antibody Target FUT4/815 + BRA-4F1
Alternate Name 3 Fucosyl N Acetyl Lactosamine; Alpha (1,3) Fucosyltransferase; Alpha 13 fucosyltransferase FucT; ELAM Ligand Fucosyltransferase; ELFT; FCT3A; Fuc-TIV; Fucosyltransferase 4 Alpha 1 3 Fucosyltransferase Myeloid Specific; Fucosyltransferase 4; Galactoside 3
Host Mouse
Antibody Type Monoclonal
Isotype Mouse / IgM's
Immunogen Purified human neutrophils (FUT4/815); Myelomonocytic leukemia cells (BRA-4F1)
Accession # P22083
Gene ID 2526
Appearance Colorless liquid
Formulation In 10 mM PBS with 0.05% BSA & 0.05% azide
Purification Purified from Bioreactor Concentrate
Species Reactivity Human
Application FC, IF, IHC
Positive Control IHC:human Hodgkin's Lymphoma
Application & Usage FC: 0.5-1 ug/1X106 cells in 0.1ml, IF: 0.5-1 ug/ml, IHC: 0.5-1 ug/ml
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin's disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.


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