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Product Details
| Cat # +Size | A1476-100 |
|---|---|
| Size | 100 µg |
| Antibody Target | FUT4/815 + BRA-4F1 |
| Alternate Name | 3 Fucosyl N Acetyl Lactosamine; Alpha (1,3) Fucosyltransferase; Alpha 13 fucosyltransferase FucT; ELAM Ligand Fucosyltransferase; ELFT; FCT3A; Fuc-TIV; Fucosyltransferase 4 Alpha 1 3 Fucosyltransferase Myeloid Specific; Fucosyltransferase 4; Galactoside 3 |
| Host | Mouse |
| Antibody Type | Monoclonal |
| Isotype | Mouse / IgM's |
| Immunogen | Purified human neutrophils (FUT4/815); Myelomonocytic leukemia cells (BRA-4F1) |
| Accession # | P22083 |
| Gene ID | 2526 |
| Appearance | Colorless liquid |
| Formulation | In 10 mM PBS with 0.05% BSA & 0.05% azide |
| Purification | Purified from Bioreactor Concentrate |
| Species Reactivity | Human |
| Application | FC, IF, IHC |
| Positive Control | IHC:human Hodgkin's Lymphoma |
| Application & Usage | FC: 0.5-1 ug/1X106 cells in 0.1ml, IF: 0.5-1 ug/ml, IHC: 0.5-1 ug/ml |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20 °C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin's disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.
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