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Anti-CD11c Antibody (HC1/1)

Monoclonal Antibody to detect CD11c in human samples
Catalog #: A1473
$395.00

Product Details

Cat # +Size A1473-100
Size 100 µg
Antibody Target CD11c
Alternate Name CD11 antigen-like family member C; Complement component 3 receptor 4 subunit; Integrin alpha-X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); Leu M5 alpha subunit; Leukocyte adhesion glycoprotein p150 95 alpha chain; Myeloid membrane antigen alpha subunit; p150/95
Host Mouse
Antibody Type Monoclonal
Isotype Mouse IgG1, kappa
Immunogen Human monocytic U937 phorbol ester-treated cells
Accession # P20702
Gene ID 3687
Appearance Colorless liquid
Formulation In 10 mM PBS with 0.05% BSA & 0.05% azide
Purification Protein A/G purification
Species Reactivity Human
Application FC, IF
Positive Control FC: human PBMC's
Application & Usage FC: 0.5-1 ug/1X106 cells, IF: 0.5-1 ug/ml
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute non-lymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.


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