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Anti-CD11a Antibody (CRIS-3)

Monoclonal Antibody to detect CD11a in human samples
Catalog #: A1472
$395.00

Product Details

Cat # +Size A1472-100
Size 100 µg
Antibody Target CD11a
Alternate Name Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide; Integrin alpha-L; ITGAL; Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain; LFA 1 alpha (LFA1A); Ly15; Ly21; p180
Host Mouse
Antibody Type Monoclonal
Isotype Mouse / Ig2b, kappa
Immunogen Stimulated human leukocytes
Accession # P20701
Gene ID 3683
Appearance Colorless liquid
Formulation In 10 mM PBS with 0.05% BSA & 0.05% azide
Purification Protein A/G purification
Species Reactivity Human
Application FC, IF
Positive Control FC: human PBMC's
Application & Usage FC: 0.5-1 ug/1X106 cells, IF: 0.5-1 ug/ml
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Recognizes a protein of 180kDa, identified as CD11a (Leucocyte Workshop II; Code N202). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses.


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