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Anti-CCR5, Humanized Antibody

Biosimilar to Leronlimab, monoclonal antibody that targets CCR5
Catalog #: A2181
$455.00

Product Details

Cat # +Size A2181-100
Size 100 μg
Antibody Target CCR5
Alternate Name CKR5, CCR-5, CD195, CKR-5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5
Host Recombinant
Antibody Type Monoclonal
Isotype IgG4, kappa
Immunogen Human CCR5
Accession # DB05941
Appearance Colorless liquid
Formulation In PBS, pH 7.5
Purification Protein A purified
Species Reactivity Human
Handling The antibody solution should be gently mixed before use.
Storage Conditions -80°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The research-grade biosimilar is a humanized IgG4 monoclonal antibody that specifically recognizes CCR5. CCR5 is a chemokine receptor that is expressed on the surface of a broad range of cells including T-cells, B-cells, and macrophages, and plays an important role in immune responses. Human Immunodeficiency Virus 1 (HIV-1) uses CCR5 as a coreceptor to enter and infect immunologic cells. The antibody binds to the hydrophilic extracellular domains of the CCR5.


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