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Anti-Caspase-3 Antibody

Polyclonal antibody to detect Caspase-3 in human mouse and rat sample.
Catalog #: A1751
$395.00

Product Details

Cat # +Size A1751-100
Size 100 µl
Antibody Target Caspase-3
Alternate Name CASP3, Caspase 3, apoptosis-related cysteine protease, CPP32B, Cysteine protease CPP32, SCA-1, SREBP cleavage activity 1
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Accession # P42574
Gene ID 836
Appearance Colorless liquid
Concentration 0.6 mg/ml
Formulation PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification Affinity purification
Species Reactivity Rat, Mouse, Human
Application Immunohistochemistry (IHC), Western Blotting, ELISA
Application & Usage WB 1:200-1:1000, IHC 1:50-1:200
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.


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