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Anti-Caspase-3 Antibody (Clone#AMC0213)

Affinity purified mouse monoclonal antibody to detect Caspase-3 expression in human and mouse samples
Catalog #: A2015
$310.00

Product Details

Size 100 µl
Antibody Target Caspase-3
Alternate Name CPP32; CPP32B; SCA-1; Active Caspase 3; CASP3; active Caspase-3; Caspase 3; Caspase-3 p12; caspase-3
Host Mouse
Antibody Type Monoclonal
Isotype IgG
Immunogen Recombinant protein of human Caspase-3
Accession # P42574
Gene ID 836
Appearance Colorless liquid
Formulation In PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Affinity purified
Species Reactivity Mouse, Human
Application Western Blotting
Application & Usage WB 1:500 - 1:2000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.


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