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Anti-Caspase-3 (Active) Biotinylated Antibody

Rabbit polyclonal antibody to detect biotinylated active Caspase 3 in human samples
Catalog #: A2116
SKU-Size Size Price Qty
A2116-30T 30 μl
$105.00
A2116-100 100 μl
$290.00
More Sizes Get Quote

Product Details

Antibody Target Caspase 3
Alternate Name CPP32; CPP32B; SCA-1; Active Caspase 3; CASP3; active Caspase-3; Caspase 3; Caspase-3 p12; caspase-3
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen Synthetic peptide mapping to the N-terminus adjacent to the cleavage site of human caspase-3
Accession # P42574
Gene ID 836
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation In PBS, pH 7.2, 30% glycerol, 0.5% BSA, 0.5 mM EDTA and 0.03% proclin
Purification Antigen Affinity purified
Species Reactivity Human
Application ELISA
Application & Usage ELISA 1:500 - 1:2000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.


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