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Anti-C-Peptide Antibody (4C2F10)

Monoclonal antibody to detect C-Peptide
Catalog #: A1361
$265.00

Product Details

Cat # +Size A1361-500
Size 500 µg
Antibody Target C-peptide
Host Mouse
Antibody Type Monoclonal
Isotype Mouse IgG1, κ
Immunogen Human C-peptide conjugated to KLH
Accession # P01308
Gene ID 3630
Appearance Colorless liquid
Formulation In PBS buffer, pH 7.4, containing 0.02% sodium azide
Purification Protein A purified
Species Reactivity Human
Application ELISA
Positive Control ELISA
Handling The antibody solution should be gently mixed before use
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

C-peptide serves as an important linker between A-chain and B-chain of insulin and facilitates the efficient assembly, folding, and processing of insulin in the endoplasmic reticulum. Equimolar amounts of C-peptide and insulin are stored in secretory granules of the pancreatic beta cells and both are eventually released to the portal circulation. The sole interest in C-peptide was as a marker of insulin secretion. Newly diagnosed diabetes patients often get their C-peptide levels measured as a means of distinguishing type 1 and type 2 diabetes. C-peptide is also used for determining the possibility of gastrinomas associated with Multiple Endocrine Neoplasm syndromes (MEN 1). C-Peptide Antibody is produced from the hybridoma resulting from fusion of SP2/0-Ag14 myeloma and B-lymphocytes obtained from mouse immunized with human C-peptide conjugated to KLH.


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