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Anti-BMP-2 Antibody

Polyclonal antibody to detect endogenous levels of BMP-2 in human, mouse and rat samples
Catalog #: A1621

In stock

$295.00

Product Details

Cat # +Size A1621-100
Size 100 µl
Antibody Target BMP-2
Alternate Name BMP2, BMP-2, BMP 2, bone morphogenetic protein 2, BMP-2A, BMP2A , BMP 2A
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BMP2
Accession # P12643
Gene ID 650
Appearance Colorless liquid
Formulation In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
Purification Affinity purified
Species Reactivity Human, Mouse, Rat
Application WB, IHC
Positive Control WB: Caco2 (A); HepG2 (B); THP1 (C) whole cell lysates, IHC: human lung cancer
Application & Usage WB; 1:500 – 1:1000, IHC: 1:100 – 1:200
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throμghout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF-beta superfamily are disulfide-linked dimmers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis. It is also expressed in a variety of tissues such as lung, spleen, brain, liver, prostate ovary and small intestine.


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