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Anti-Bcl-X Antibody (2H12)

Monoclonal antibody to detect Bcl-X in human, mouse, rat and pig samples
Catalog #: A1438

In stock

$325.00

Product Details

Cat # +Size A1438-100
Size 100 µg
Antibody Target Bcl-X
Alternate Name Apoptosis regulator Bcl-X, B cell lymphoma 2 like, BCL XL/S, Bcl-2-like protein 1, Bcl2-L-1, BCL2L, Bcl2l1, BCLX, BclXL, BclXs, Protein phosphatase 1 regulatory subunit 52 (PPP1R52)
Host Mouse
Antibody Type Monoclonal
Isotype Mouse IgG2a
Immunogen A synthetic peptide, aa 3-14 (Cys-QSNRELVVDFLS) of human Bcl-X protein
Accession # Q07817
Gene ID 598
Appearance Colorless liquid
Formulation In 10 mM PBS with 0.05% BSA & 0.05% azide
Purification Protein A/G purification
Species Reactivity Human, Mouse, Rat, Pig
Application FC, IF, IHC, WB
Positive Control WB: Jurkat cell lysate, IHC: human Hodgkin's Lymphoma
Application & Usage FC: 0.5-1 ug/1X106 cells, IF: 0.5-1 ug/ml, WB: 0.5-1ug/ml, IHC: 0.5-1 ug/ml
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Recognizes a protein of 27 kDa, identified as the Bcl-X protein. This MAb shows no cross-reaction with Bcl-2 or Bax protein. Bcl-X has two isoforms, Bcl-XL (long), a 241 amino acid protein which suppresses cell death. And Bcl-XS (short), a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl-2. This MAb reacts with both Bcl-XS and Bcl-XL proteins.


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