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Anti-APIP Antibody

Polyclonal antibody to detect APIP in human and mouse samples.
Catalog #: A1766
$395.00

Product Details

Cat # +Size A1766-100
Size 100 μl
Antibody Target APAF1-interacting protein
Alternate Name Apaf1 Interacting Protein, APIP2, CG129, Monocyte/macrophage protein 19, MTNB, dJ179L10.2
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Accession # Q96GX9
Gene ID 51074
Appearance Colorless liquid
Concentration 0.2 mg/ml
Formulation PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification Affinity purification
Species Reactivity Mouse, Human
Application Immunohistochemistry (IHC), Western Blotting
Application & Usage WB 1:200-1:1000, IHC 1:25-1:100
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury.The protein highly expressed in skeletal muscle and heart and binds to the CARD of Apaf-1 in competition with caspase-9. Exogenous APIP inhibits cytochrome c-induced activation of caspase-3 and caspase-9, and suppresses cell death triggered by mitochondrial apoptotic stimuli through inhibiting the downstream activity of cytochrome c released from mitochondria.


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