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New

Anti-AFP Antibody (C3)

Monoclonal antibody to detect AFP human monkey and rat samples
Catalog #: A1423

In stock

$325.00

Product Details

Cat # +Size A1423-100
Size 100 µg
Antibody Target Alpha Fetoprotein
Alternate Name Alpha fetoglobulin, FETA, HPAFP
Host Mouse
Antibody Type Monoclonal
Isotype Mouse IgG2b, kappa
Immunogen Alpha fetoprotein (AFP) purified from serum of a hepatoma patient
Accession # P02771
Gene ID 174
Appearance Colorless liquid
Formulation In 10 mM PBS with 0.05% BSA & 0.05% azide
Purification Protein A/G purification
Species Reactivity Human, Monkey, Rat
Application FC, IF, IHC
Positive Control IHC:Fetal liver tissue
Application & Usage FC: 0.5-1 ug/1X106 cells in 0.1 ml, IF: 0.5-1 ug/ml, IHC: 1-2 ug/ml
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

This antibody recognizes an oncofetal glycoprotein with a single chain of 70 kDa, which is identified as alpha-fetoprotein (AFP) (ISOBM TD-2 workshop). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.


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