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Anti-ADD1 Antibody

Polyclonal antibody to detect Anti-ADD1 Antibody in human, mouse and rat samples.
Catalog #: A1744
$395.00

Product Details

Cat # +Size A1744-100
Size 100 µl
Antibody Target Alpha-adducin
Alternate Name ADDA, Adducin 1 (alpha), Alpha adducin, Alpha-adducin, Erythrocyte adducin alpha subunit, Erythrocyte adducin subunit
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Accession # P35611
Gene ID 118
Appearance Colorless liquid
Concentration 0.4 mg/ml
Formulation PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification Affinity purification
Species Reactivity Rat, Mouse, Human
Application Immunohistochemistry (IHC)
Application & Usage IHC 1:50-1:200
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.


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